Abstract: Sepsis, a critical illness in which the body responds abnormally to infection, has a high rate of morbidity and mortality and poses a serious threat to human life and health.However, the clinical diagnosis of sepsis is still lagging behind, and its heterogeneity and lack of specific manifestations pose significant challenges to its management.In recent years, artificial intelligence has made some breakthroughs in the early prediction, clinical phenotype, and precise treatment of sepsis, contributing to the construction of an intelligent clinical decision-making system and a new system for sepsis diagnosis and treatment.This review summarizes recent advances in artificial intelligence technology for the intelligent management of sepsis patients in the hope of providing some reference for further research.