创新链/学科链/研发链/产业链

新药研发前沿动态 / 医药领域趋势进展

杨安平, 曹雨, 刘莹, 赵超超, 李舟. 基于纳米发电机的自驱动技术控制药物释放的研究进展[J]. 药学进展, 2021, 45(4): 314-附页4.
引用本文: 杨安平, 曹雨, 刘莹, 赵超超, 李舟. 基于纳米发电机的自驱动技术控制药物释放的研究进展[J]. 药学进展, 2021, 45(4): 314-附页4.
YANG Anping, CAO Yu, LIU Ying, ZHAO Chaochao, LI Zhou. Progress of Research on Nanogenerator-Based Selfpowered Technology for Drug Controlled Release[J]. Progress in Pharmaceutical Sciences, 2021, 45(4): 314-附页4.
Citation: YANG Anping, CAO Yu, LIU Ying, ZHAO Chaochao, LI Zhou. Progress of Research on Nanogenerator-Based Selfpowered Technology for Drug Controlled Release[J]. Progress in Pharmaceutical Sciences, 2021, 45(4): 314-附页4.

基于纳米发电机的自驱动技术控制药物释放的研究进展

Progress of Research on Nanogenerator-Based Selfpowered Technology for Drug Controlled Release

  • 摘要: 基于纳米发电机的自驱动技术自被提出以来得到了迅速发展,该技术可将人体生命活动中的机械能转化为电能,可用于自驱动的生理信号监测、电子医疗器件和药物可控释放等。综述自驱动技术在微针药物释放、膜控型药物释放、电穿孔药物释放、微流控药物释放及电化学药物释放等方面的研究成果,并探讨自驱动的药物控制释放技术应用于临床治疗面临的挑战和未来精准医疗研究方向。

     

    Abstract: Self-powered technology based on nanogenerator, which has developed rapidly since it emerged, can convert mechanical energy of human movement and life activities into electrical energy, which can be used for self-powered physiological signal monitoring, electronic medical devices and controlled drug release. This paper summarizes the latest research progress of drug controlled release application using self-powered technology combined with microneedle, membrane, electroporation, microfluidics and electrochemistry, and proposes the research directions of future precision therapy and challenges for the clinical application of self-powered drug release systems.

     

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