创新链/学科链/研发链/产业链

新药研发前沿动态 / 医药领域趋势进展

基于“补”“清”一体理论的针药结合疗法对气血两虚型女性产后压力性尿失禁的影响

The Effect of Combined Acupuncture and Herbal Medicine Therapy Based on the Integrated "Tonifying and Clearing" Theory on Postpartum Stress Urinary Incontinence in Patients with Qi and Blood Deficiency Pattern

  • 摘要: 目的 探讨基于“补”“清”一体理论的针药结合疗法治疗气血两虚型女性产后压力性尿失禁(stress urinaryincontinence,SUI)的疗效。方法 选择2023年1月至2024年6月上海市徐汇区大华医院接诊的78例产后SUI患者,按照随机数字表法分为A组、B组和C组,每组26例。A组采用基于“补”“清”一体理论的针药结合疗法+Kegel运动疗法,B组采用针刺+Kegel运动疗法,C组采用单纯Kegel运动疗法,3组均持续治疗4周。比较3组治疗4周后的临床疗效、盆底肌力、最大尿流率(maximum flow rate,Qmax)、腹压漏尿点压(abdominal leak point pressure,ALPP)、最大尿道闭合压力(maximumurethral closure pressure,MUCP)、盆底障碍影响简易问卷-7(Pelvic Floor Distress Impact Questionnaire-7,PFIQ-7)、盆腔脏器脱垂/尿失禁性功能问卷-12(Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire-12,PISQ-12),以及随访3个月的复发率。结果 治疗4周后,A组总有效率高于C组,有统计学意义(P<0.05);治疗2周和4周后,A组的盆底肌力优于C组(P<0.05),A组的Qmax、ALPP、MUCP高于B组、C组,且B组以上指标高于C组(P<0.05),A组的PFIQ-7评分、PISQ-12评分低于B组、C组,且B组以上指标低于C组(P<0.05)。对在临床治疗中获得显效及有效的患者进行3个月随访,A组、B组的复发率低于C组(P<0.05)。结论 基于“补”“清”一体理论的针药结合疗法治疗气血两虚型女性产后SUI的疗效明显,有助于改善患者的盆底肌力和尿动力学,降低复发率。

     

    Abstract: Objective To investigate the efficacy of combined acupuncture and herbal medicine therapy based on the "Tonifying and Clearing" theory, for the management of postpartum stress urinary incontinence (SUI) with the qi and blood deficiency pattern. Methods A total of 78 postpartum SUI patients admitted to Dahua Hospital, Xuhui District, between January 2023 and June 2024 were selected and randomly divided into Group A, B, and C, according to a random number table, with 26 patients in each group. Group A received combined acupuncture and herbal medicine based on the "Tonifying and Clearing" theory plus Kegel exercises therapy, Group B received acupuncture plus Kegel exercises therapy, and Group C received Kegel exercises therapy alone. All three groups were treated continuously for 4 weeks. Comparisons were made among the three groups for the following items after 4 weeks of treatment: clinical efficacy, pelvic floor muscle strength, maximum flow rate (Qmax), abdominal leak point pressure (ALPP), maximum urethral closure pressure (MUCP), Pelvic Floor Distress Impact Questionnaire-7 (PFIQ-7) and Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire-12 (PISQ- 12) scores, along with the recurrence rate at the 3-month follow-up. Results After 4 weeks of treatment, the total effective rate in Group A was significantly higher than that in Group C (P<0.05). After 2 and 4 weeks of treatment, the pelvic floor muscle strength in Group A was superior to that in Group C (P<0.05). The Qmax, ALPP, and MUCP in Group A were higher than those in Group B and Group C, and these indicators in Group B were higher than those in Group C (P<0.05). The PFIQ-7 and PISQ-12 scores in Group A were lower than those in Group B and Group C, and these scores in Group B were lower than those in Group C (P<0.05). Patients who achieved marked effectiveness or effectiveness in clinical treatment were followed up for 3 months. Group A and Group B both had a lower recurrence rate than Group C (P<0.05). Conclusion The combined acupuncture and herbal medicine therapy based on the "Tonifying and Clearing" theory demonstrates significant efficacy for the treatment of postpartum SUI with the qi and blood deficiency pattern, improving pelvic floor muscle strength and urodynamic parameters, and reducing the recurrence rate.

     

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