Abstract: Through analysis of the global and China’s patent applications of antibody-drug conjugates (ADCs), this paper attempts to help researchers understand the development trend of the techniques in China and around the globe. From the perspectives of target and small molecule toxins, the development trend of ADCs-related techniques as well as the current hot targets and small molecule toxins were analyzed. In addition, the patent layout of the main patent applicants related to ADCs techniques was introduced. Through the above statistical analysis, the article provides reference and insights for China’s domestic enterprises to enhance their comprehensive competitiveness in ADCs-related techniques.