创新链/学科链/研发链/产业链

新药研发前沿动态 / 医药领域趋势进展

WANG Huating, YU Caini, KANG Yuanyuan, LI Dan. Progress of Research on the Mechanism of Action of Traditional Chinese Medicine Monomers in Prostate Cancer Intervention[J]. Progress in Pharmaceutical Sciences, 2022, 46(12): 951-960. DOI: 10.20053/j.issn1001-5094.2022.12.007
Citation: WANG Huating, YU Caini, KANG Yuanyuan, LI Dan. Progress of Research on the Mechanism of Action of Traditional Chinese Medicine Monomers in Prostate Cancer Intervention[J]. Progress in Pharmaceutical Sciences, 2022, 46(12): 951-960. DOI: 10.20053/j.issn1001-5094.2022.12.007

Progress of Research on the Mechanism of Action of Traditional Chinese Medicine Monomers in Prostate Cancer Intervention

  • Prostate cancer (PCa), a common malignancy in men worldwide, has a high rate of morbidity and mortality in China. With their confirmed structures and rich sources, traditional Chinese medicine (TCM) monomers have their special advantages for developing anti-PCa drugs. This study reviews the action mechanisms of TCM monomers in the treatment of PCa from androgen receptor (AR) dependence and AR independence, so as to provide some reference for the exploration of specific PCa therapeutic regimens using TCM and useful information for the development of novel drugs treating PCa.
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