Research Progress of Platelet-derived Growth Factors and Their Receptors in Tumor

Platelet-derived growth factor (PDGF) and PDGFR (platelet-derived growth factor receptor) play an important role in angiogenesis and cell mitosis, and affect the development and metastasis of tumor in several ways. This review summarizes the advances in research on the effects of PDGF/PDGFR on tumor progression tracking by the cell types in tumor environment, and the clinical research breakthroughs of related drugs in recent years, aiming to provide reference for tumor treatment.