Research Progress in Biological Monitoring and Diagnosis Based on Microneedles

Microneedles (MNs) have emerged in the field of transdermal drug delivery due to their advantages of convenience, minimal invasiveness, and painlessness. In recent years, with the development of point-of-care testing (POCT), integrated microneedles in combination with sampling and real-time biomarker detection have received increasing attention in scientific research and medical service. This review summarizes the classification of microneedle-mediated diagnostic strategies, the types of samples that can be extracted by microneedles, and microneedle-mediated biomonitoring and diagnosis, with a prospect to the future development and application of microneedle-mediated biomonitoring and diagnosis.