Advances in Research on the Role of Sacchariderelated Molecules in Diseases

Sugar chains and related molecules (including glycan transferase, glycoside hydrolase and glycan binding protein) in living organisms are closely related to health and diseases. The glycosylation of protein and lipid is an important post-translational modification process in cells, which is completed by glycosyltransferase and glycoside hydrolase. The relevance of its process to infections, tumors and other diseases is attracting more and more attention. Studies have shown that in the progress of cancer, the expression levels of glycosylation-related genes have changed significantly. The glycan biosynthesis pathways provide new insights for the diagnosis and treatment of cancer, infection and genetic diseases. This review summarizes the advances in research on the role of saccharide-related molecules in diseases.