Advances on Pharmacokinetic Researches on Aporphine Alkaloids

Aporphine alkaloids belonging to the isoquinoline alkaloid family is a natural product existing widely in nature. Modern pharmacological studies have found that aporphine alkaloids possess a lot of pharmacological activities such as anti-oxidation, anti-tumor and anti-rheumatis, therefore, the pharmacokinetic studies of aporphine alkaloids play a significant role in guiding the development of clinical drugs and new drug preparations. This paper summarizes the pharmacokinetic studies of several common aporphine alkaloids, with an aim to provide reference for further investigation of the pharmacokinetics of aporphine alkaloids.