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新药研发前沿动态 / 医药领域趋势进展

YE Jiadan, YU Kefu, ZHU Bin, SI Yanbin, ZHAO Zhigang. Classification and Research Progress of Targeted Anti-tumor Drugs[J]. Progress in Pharmaceutical Sciences, 2018, 42(5): 351-358.
Citation: YE Jiadan, YU Kefu, ZHU Bin, SI Yanbin, ZHAO Zhigang. Classification and Research Progress of Targeted Anti-tumor Drugs[J]. Progress in Pharmaceutical Sciences, 2018, 42(5): 351-358.

Classification and Research Progress of Targeted Anti-tumor Drugs

  • With the progress of molecular biology, targeted tumor therapy has become a hot research topic in cancer treatment, with increased number of targeted drugs entering clinical trials. According to their nature, targeted drugs can be mainly grouped into two categories: monoclonal antibody and single targeted or multi-targeted small molecule inhibitors. This article summarizes the classification and characteristics of various targeted drugs for common tumors such as lung cancer, breast cancer and colorectal cancer, explores the research progresses of anti-tumor drugs and compares the approval status and indications of targeted drugs between China and the United States.
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